Thrombotic risk assessment in APS: the Global APS Score (GAPSS)
نویسندگان
چکیده
منابع مشابه
The global anti-phospholipid syndrome score in primary APS.
OBJECTIVE The aim of this study was to evaluate the clinical relevance of the global APS score (GAPSS) in a cohort of primary APS patients. METHODS This study included 62 consecutive patients with primary APS. Data on clinical manifestations, conventional cardiovascular risk factors and aPL profile were collected. The GAPSS was calculated for each patient by adding together the points corresp...
متن کاملGAPSS: the Global Anti-Phospholipid Syndrome Score.
OBJECTIVE To develop and validate a risk score [global APS score (GAPSS)] derived from the combination of independent risk for thrombosis and pregnancy loss (PL), taking into account the aPL profile, conventional cardiovascular risk factors and the autoimmune antibody profile. METHODS This cross-sectional study included 211 consecutive SLE patients. Data on clinical manifestations, convention...
متن کاملPathophysiology of thrombotic APS: where do we stand?
The antiphospholipid syndrome (APS) is diagnosed when patients with thrombotic complications or foetal losses have elevated levels of antiphospholipid antibodies in their plasmas. The term APS is confusing, because the pathogenic auto-antibodies are not directed against phospholipids but towards a plasma protein, β(2)-glycoprotein I. For many years the reason why auto-antibodies against β(2)-gl...
متن کاملComputations in APS
Algebraic programming system APS integrates four main paradigms of computations: procedural , functional, algebraic (rewriting rules) and logical. All of them may be used in diierent combinations on diierent levels of implementation. Formal models used in the developing computational techniques for APS are presented and discussed. It includes data structures, algebraic modules, rewriting and co...
متن کاملPathogenetic mechanisms in APS
Antiphospholipid syndrome is diagnosed when arterial or venous thrombosis or recurrent miscarriages occur in a person in whom laboratory tests for antiphospholipid antibodies (anticardiolipin antibodies and/or lupus anticoagulant and/or anti-beta 2-glycoprotein I) are positive. Despite the strong association between antiphospholipid antibodies and thrombosis, their pathogenic role in the develo...
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ژورنال
عنوان ژورنال: Lupus
سال: 2014
ISSN: 0961-2033,1477-0962
DOI: 10.1177/0961203314541317